ICU sedation, delirium & recovery
Diagnostic accuracy of multi-organ point-of-care ultrasound for pulmonary embolism in critically ill patients: a systematic review and meta-analysis
Authors' conclusion
Multi-organ POCUS has high diagnostic accuracy for PE diagnosis in critically ill patients.
Study context
- Population
- Critically ill patients with suspected pulmonary embolism (PE) in critical care departments
- Participants
- 594 patients · 4 studies
- Comparison
- Multi-organ point-of-care ultrasound (POCUS) vs computed tomography pulmonary angiography (CTPA) or ventilation-perfusion scan
- Outcome
- Diagnostic accuracy of multi-organ POCUS for PE (pooled DOR, sensitivity, specificity, PLR, NLR, SROC)
Methodological detailsbivariate random-effects model, QUADAS-2 quality assessment
- Bivariate random-effects model
- QUADAS-2 quality assessment
Pooled result
As reported in the abstract
Diagnostic accuracy for PE
| Group | Pooled diagnostic odds ratio (DOR) | Pooled sensitivity | Specificity | Positive likelihood ratio (PLR) | Negative likelihood ratio (NLR) | Summary receiver operating characteristic (SROC) AUC |
|---|---|---|---|---|---|---|
| Multi-organ POCUS | 25.3 (95% CI 4.43-82.9) | 0.90 (95% CI 0.85-0.94; I2 = 0%) | 0.69 (95% CI 0.42-0.87; I2 = 95%) | 3.35 (95% CI 1.43-8.02) | 0.16 (95% CI 0.08-0.32) | 0.89 (95% CI 0.81-0.94) |
Multi-organ POCUS
Pooled diagnostic odds ratio (DOR)25.3 (95% CI 4.43-82.9)
Pooled sensitivity0.90 (95% CI 0.85-0.94; I2 = 0%)
Specificity0.69 (95% CI 0.42-0.87; I2 = 95%)
Positive likelihood ratio (PLR)3.35 (95% CI 1.43-8.02)
Negative likelihood ratio (NLR)0.16 (95% CI 0.08-0.32)
Summary receiver operating characteristic (SROC) AUC0.89 (95% CI 0.81-0.94)
Original publication
Diagnostic accuracy of multi-organ point-of-care ultrasound for pulmonary embolism in critically ill patients: a systematic review and meta-analysis. Crit Care. Published 23 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →