Diagnostic Accuracy of Vascular Ultrasonography for Postanesthesia Induction Hypotension: A Systematic Review and Network Meta-Analysis

Anesth AnalgPublished Systematic review and network meta-analysis of diagnostic test accuracy studies

Authors' conclusion

The predictive performance of point-of-care ultrasound for PIH is uncertain.

Study context

Population
Adults in noncardiac, nonobstetrical routine surgery
Participants
2,631 adults · 32 studies
Comparison
Point-of-care ultrasound tests for predicting postinduction hypotension
  • Inferior vena cava collapsibility indexn = 22 studies
  • Carotid artery corrected flow timen = 2 studies
Outcome
Postinduction hypotension (PIH) as defined by study authors
Methodological detailsBayesian, Cochrane methodology, QUADAS-2, Grading of Recommendations Assessment, Development and Evaluation (GRADE)
  • Bayesian
  • Cochrane methodology
  • QUADAS-2
  • GRADE

Pooled result

As reported in the abstract

Predictive performance for PIH
GroupSensitivitySpecificity
Inferior vena cava collapsibility index60% (95% CrI, 49%-72%)
83% (CrI, 74%-89%)Specificity on a scale from 0 to 100 percent
Carotid artery corrected flow time
91% (CrI, 76%-98%)Sensitivity on a scale from 0 to 100 percent
90% (CrI, 59%-98%)Specificity on a scale from 0 to 100 percent

Sensitivity

Inferior vena cava collapsibility index60% (95% CrI, 49%-72%)
Carotid artery corrected flow time91% (CrI, 76%-98%)
Sensitivity on a scale from 0 to 100 percent

Specificity

Inferior vena cava collapsibility index83% (CrI, 74%-89%)
Carotid artery corrected flow time90% (CrI, 59%-98%)
Specificity on a scale from 0 to 100 percent

Further pooled results

Risk of bias and certainty of evidence

Serious bias and applicability concerns (selection bias, inappropriate blinding)
Certainty of evidence very low for all tests

Original publication

Diagnostic Accuracy of Vascular Ultrasonography for Postanesthesia Induction Hypotension: A Systematic Review and Network Meta-Analysis. Anesth Analg. Published 6 June 2025. doi:10.1213/ane.0000000000007108

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