Cardiac arrest & resuscitation

Diagnostic yield, safety, and outcomes of Head-to-pelvis sudden death CT imaging in post arrest care: The CT FIRST cohort study

ResuscitationPublished Prospective observational pre-/post-cohort study

Authors' conclusion

SDCT scanning early after OHCA resuscitation safely improved the efficiency and diagnostic yield for causes of arrest compared to the standard of care alone.

Study context

Population
Patients successfully resuscitated from of hospital circulatory arrest (OHCA) with unknown cause, age >18 years, stable for CT, no known cardiomyopathy or obstructive CAD
Participants
104 vs 143
Exposure
Head-to-pelvis sudden death CT (SDCT) added to standard of care vs standard of care (SOC) alone
  • SDCTn = 104
  • SOCn = 143reference
Outcome
SDCT diagnostic yield (causes of arrest identified)

Main finding

As reported in the abstract

Causes of arrest identified

P < 0.001

Observational data: associations, not effects.

Secondary outcomes

Time to diagnosis

reduction 78% · P < 0.0001

CT use in SOC
52% · 74 of 143

Critical diagnoses

SDCT reduced delayed (>6 hours) identification of critical diagnoses
81%; p < 0.001
Identification of critical diagnoses similar between cohorts

Survival to discharge

Similar between cohorts

Safety

SDCT safety endpoints incl. AKI

Safety endpoints, including AKI, similar between cohorts

Original publication

Diagnostic yield, safety, and outcomes of Head-to-pelvis sudden death CT imaging in post arrest care: The CT FIRST cohort study. Resuscitation. Published 3 April 2023. doi:10.1016/j.resuscitation.2023.109785

Composed by AI from the published abstract and checked against it. How Briefs are made →

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