Perioperative medicine & outcomes
Discordances between Preoperative Creatinine- and Cystatin C–based Estimated Glomerular Filtration Rate and Outcomes after Noncardiac Surgery: An Observational Study
Authors' conclusion
More negative preoperative eGFRdiff was independently associated with higher risk of postoperative complications in Asian patients undergoing noncardiac surgery.
Study context
- Population
- Patients undergoing major noncardiac surgery at two large hospitals in China
- Participants
- 35,488 vs 23,417
- Exposure
- More negative vs less negative preoperative eGFRdiff
- Nanfangn = 35,488
- Xinjiangn = 23,417
- Outcome
- Composite of:
- Postoperative complications
- Death
Methodological detailstwo hospitals
- Two hospitals
Main finding
As reported in the abstract
Nanfang
8.4
%
Xinjiang
14.4%
Adjusted odds ratio per 10 ml · min -1 · 1.73 m -2 decrease in eGFRdiff (95% CI)P value
Nanfang
1.12(1.09–1.15)
P < 0.001Xinjiang
1.11(1.09–1.14)
P < 0.001Observational data: associations, not effects.
Further findings
Component outcomes (cardiovascular events, AKI, infections, pulmonary complications, death)
- Associations also observed across categories of component outcomes
Original publication
Discordances between Preoperative Creatinine- and Cystatin C–based Estimated Glomerular Filtration Rate and Outcomes after Noncardiac Surgery: An Observational Study. Anesthesiology. Published 10 March 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →