Double dural puncture epidural improves quality of labour analgesia without increasing adverse effects in primipara: A randomised controlled trial
Authors' conclusion
Compared with the epidural technique, DDPE showed significant advantages for the onset of labour analgesia and demonstrated good efficacy in sacral coverage, which may improve the quality of the neuraxial block and better meet the demand for rapid analgesia in labouring women.
Study context
- Population
- Primipara receiving neuraxial labour analgesia, Huai'an First People's Hospital, June 2023 to March 2024
- Participants
- 120 participants
- Comparison
- Double dural puncture epidural (DDPE) vs epidural for labour analgesia
- Primary endpoint
- Proportion with adequate analgesia (VAS pain score ≤ 30 mm)
- Follow-up
- 10 min after the neuraxial block (T1)
Methodological detailssingle-centre, prospective, single-blind
- Single-centre
- Prospective
- Single-blind
Primary result
As reported in the abstract
T1
DDPE
75.0
%
Epidural
40.0%
P < 0.001
Secondary outcomes
Adequate analgesia · T3
P = 0.017
Need for additional analgesia
P = 0.014
Onset of sacral coverage
P < 0.001
Drug consumption
P = 0.005
| Outcome | DDPE | Epidural | P value |
|---|---|---|---|
| Pain VAS score · T1 | 26 (range 20–34.5) | 48 (range 26–59.5) | P < 0.001 |
| Pain VAS score · T4 | 36.5 (range 29–48.5) | 44.5 (range 30–59.8) | P = 0.01 |
Safety
| Outcome | P value |
|---|---|
| Adverse reactions | P > 0.05 |
Adverse reactions
- No significant difference between DDPE and epidural
Original publication
Double dural puncture epidural improves quality of labour analgesia without increasing adverse effects in primipara: A randomised controlled trial. Eur J Anaesthesiol. Published 21 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →