Cardiac arrest & resuscitation

Early ADL ability assessment and cognitive screening as markers of post-discharge outcomes after surviving an out-of-hospital cardiac arrest. A prospective cohort study

ResuscitationPublished Prospective cohort study

Authors' conclusion

Decreased ADL ability at hospital discharge was associated with poorer post-discharge outcomes in OHCA survivors, while cognitive screening was also associated with certain aspects of recovery.

Study context

Population
Out-of-hospital cardiac arrest (OHCA) survivors admitted to Aarhus University Hospital
Participants
200 survivors
Exposure
ADL ability measures (Activities of Daily Living Interview (ADL-I), Assessment of Motor and Process Skills (AMPS)) and cognitive screening (Montreal Cognitive Assessment (MoCA)) at hospital discharge as markers of post-discharge outcomes
Outcome
Post-discharge ADL ability, HRQoL and return to work
Methodological detailsmultiple imputation, multivariable regression
  • Multiple imputation
  • Multivariable regression

Main finding

As reported in the abstract

Self-reported ADL ability · six months after cardiac arrest

Personal ADL-I at discharge, βadjusted

0.3

95% CI 0.2;0.5

AMPS at discharge, βadjusted

−0.6

95% CI −1.2;−0.03

Observational data: associations, not effects.

Further findings

Return to work (MoCA) · one-year after cardiac arrest

OR (95% CI)P value
MoCA3.0 (0.5–9.0)P = 0.06
OutcomeORadjusted (95% CI)
Age-matched ADL ability (AMPS at baseline) · six months after cardiac arrest5.5 (1.5–10.0)

Health-related quality of life (HRQoL)

Personal ADL-I, VAS: βadjusted
3.00 (95% CI 1.3;4.6)
Personal ADL-I, index score: βadjusted
0.03 (95% CI 0.01;0.05)
MoCA, index: βadjusted
−0.09 (95% CI −0.2;−0.02)

Original publication

Early ADL ability assessment and cognitive screening as markers of post-discharge outcomes after surviving an out-of-hospital cardiac arrest. A prospective cohort study. Resuscitation. Published 21 May 2025. doi:10.1016/j.resuscitation.2025.110653

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