Cardiac arrest & resuscitation
Early ADL ability assessment and cognitive screening as markers of post-discharge outcomes after surviving an out-of-hospital cardiac arrest. A prospective cohort study
Authors' conclusion
Decreased ADL ability at hospital discharge was associated with poorer post-discharge outcomes in OHCA survivors, while cognitive screening was also associated with certain aspects of recovery.
Study context
- Population
- Out-of-hospital cardiac arrest (OHCA) survivors admitted to Aarhus University Hospital
- Participants
- 200 survivors
- Exposure
- ADL ability measures (Activities of Daily Living Interview (ADL-I), Assessment of Motor and Process Skills (AMPS)) and cognitive screening (Montreal Cognitive Assessment (MoCA)) at hospital discharge as markers of post-discharge outcomes
- Outcome
- Post-discharge ADL ability, HRQoL and return to work
Methodological detailsmultiple imputation, multivariable regression
- Multiple imputation
- Multivariable regression
Main finding
As reported in the abstract
Self-reported ADL ability · six months after cardiac arrest
Personal ADL-I at discharge, βadjusted
0.3
95% CI 0.2;0.5
AMPS at discharge, βadjusted
−0.6
95% CI −1.2;−0.03
Observational data: associations, not effects.
Further findings
Return to work (MoCA) · one-year after cardiac arrest
| OR (95% CI) | P value | ||
|---|---|---|---|
| MoCA | 3.0 (0.5–9.0) | P = 0.06 | |
| 0.10.31310Odds ratio (log scale) |
| Outcome | ORadjusted (95% CI) |
|---|---|
| Age-matched ADL ability (AMPS at baseline) · six months after cardiac arrest | 5.5 (1.5–10.0) |
Health-related quality of life (HRQoL)
- Personal ADL-I, VAS: βadjusted
- 3.00 (95% CI 1.3;4.6)
- Personal ADL-I, index score: βadjusted
- 0.03 (95% CI 0.01;0.05)
- MoCA, index: βadjusted
- −0.09 (95% CI −0.2;−0.02)
Original publication
Early ADL ability assessment and cognitive screening as markers of post-discharge outcomes after surviving an out-of-hospital cardiac arrest. A prospective cohort study. Resuscitation. Published 21 May 2025. doi:10. 1016/ j. resuscitation. 2025. 110653
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