Pediatric anesthesia & critical care

EEG response to a high volume (1.5 mL/kg) caudal block in infants less than 3 months

Reg Anesth Pain MedPublished Prospective observational study

Authors' conclusion

A high-volume caudal block appears to increase intracranial pressure, thereby reducing cerebral blood flow, to the extent that it transiently will affect cerebral function as assessed by EEG (increased delta power activity) in approximately 90% of small infants.

Study context

Population
Infants (0–3 months) scheduled for inguinal hernia repair
Participants
11 infants
Outcome
EEG changes (relative delta power) after high-volume caudal block
Follow-up
20 min observation period
Methodological detailssingle-group
  • Single-group

Main finding

As reported in the abstract

Transient EEG changes (mainly increased relative delta power) · initial 5-10 min postinjection
All infants displayed transient EEG changes, mainly increased relative delta power
11

Observational data: associations, not effects.

Further findings

HR and BP remained stable throughout the study

Original publication

EEG response to a high volume (1.5 mL/kg) caudal block in infants less than 3 months. Reg Anesth Pain Med. Published 26 June 2023. doi:10.1136/rapm-2023-104452

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