Perioperative medicine & outcomes

Effect of perioperative pain neuroscience education in people undergoing surgery for lumbar radiculopathy: a multicentre randomised controlled trial

Br J AnaesthPublished Randomised controlled trial

Authors' conclusion

Perioperative pain neuroscience education showed superior clinical and cost-effectiveness than perioperative biomedical education in people undergoing surgery for lumbar radiculopathy.

Study context

Population
People undergoing surgery for lumbar radiculopathy in 3 Belgian hospitals
Participants
58 vs 62
Comparison
Perioperative pain neuroscience education (PPNE) vs PBE
  • PPNEn = 58
  • PBEn = 62reference
Primary endpoint
Pain (VAS + quantitative sensory testing)
Follow-up
12 months
Methodological detailsmulticentre, balanced interventions, Randomised Mar 2016–Apr 2020, Assessments at 3 days, 6 weeks, 6 and 12 months after surgery
  • Multicentre
  • Balanced interventions
  • Randomised Mar 2016–Apr 2020
  • Assessments at 3 days, 6 weeks, 6 and 12 months after surgery

Primary result

As reported in the abstract

Pain
  • PPNE did not lead to significantly better pain outcomes

Further findings

OutcomeAdditional increase (95% CI)
36-item Short Form Health Survey physical component · 12 monthsMedium effect46.94 (14.16–79.73)

Work resumption (females) (subgroup) · higher probability for work resumption in PPNE females

OutcomeAdditional decrease (95% CI)
Tampa Scale of Kinesiophobia · 12 monthsSmall effect3.15 (0.25–6.04)
Pain Catastrophising Scale · 12 monthsMedium effect6.18 (1.97–10.39)

Cost-effectiveness

Incremental costs
€−2732
Incremental quality-adjusted life years
0.012
PPNE cost-effective vs PBE

Original publication

Effect of perioperative pain neuroscience education in people undergoing surgery for lumbar radiculopathy: a multicentre randomised controlled trial. Br J Anaesth. Published 19 June 2023. doi:10.1016/j.bja.2023.05.007

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