Perioperative medicine & outcomes
Effect of perioperative pain neuroscience education in people undergoing surgery for lumbar radiculopathy: a multicentre randomised controlled trial
Authors' conclusion
Perioperative pain neuroscience education showed superior clinical and cost-effectiveness than perioperative biomedical education in people undergoing surgery for lumbar radiculopathy.
Study context
- Population
- People undergoing surgery for lumbar radiculopathy in 3 Belgian hospitals
- Participants
- 58 vs 62
- Comparison
- Perioperative pain neuroscience education (PPNE) vs PBE
- PPNEn = 58
- PBEn = 62reference
- Primary endpoint
- Pain (VAS + quantitative sensory testing)
- Follow-up
- 12 months
Methodological detailsmulticentre, balanced interventions, Randomised Mar 2016–Apr 2020, Assessments at 3 days, 6 weeks, 6 and 12 months after surgery
- Multicentre
- Balanced interventions
- Randomised Mar 2016–Apr 2020
- Assessments at 3 days, 6 weeks, 6 and 12 months after surgery
Primary result
As reported in the abstract
Pain
- PPNE did not lead to significantly better pain outcomes
Further findings
| Outcome | Additional increase (95% CI) | |
|---|---|---|
| 36-item Short Form Health Survey physical component · 12 monthsMedium effect | 46.94 (14.16–79.73) | |
| −50050100Difference (linear scale) |
Work resumption (females) (subgroup) · higher probability for work resumption in PPNE females
| Outcome | Additional decrease (95% CI) |
|---|---|
| Tampa Scale of Kinesiophobia · 12 monthsSmall effect | 3.15 (0.25–6.04) |
| Pain Catastrophising Scale · 12 monthsMedium effect | 6.18 (1.97–10.39) |
Cost-effectiveness
- Incremental costs
- €−2732
- Incremental quality-adjusted life years
- 0.012
- PPNE cost-effective vs PBE
Original publication
Effect of perioperative pain neuroscience education in people undergoing surgery for lumbar radiculopathy: a multicentre randomised controlled trial. Br J Anaesth. Published 19 June 2023. doi:10. 1016/ j. bja. 2023. 05. 007
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