The effectiveness of a transitional pain service in patients undergoing surgery with an increased risk of developing chronic postsurgical pain (TRUSt study). A randomized clinical trial
Authors' conclusion
TPS did not significantly affect short-term quality of recovery but might improve long-term outcomes, such as the incidence of chronic pain, opioid consumption, and functioning in daily life.
Study context
- Population
- Adults (≥18 years) undergoing elective surgery with increased risk of chronic postsurgical pain (CPSP), tertiary hospital in the Netherlands169 (96.0%) with primary outcome
- Participants
- 176 adults
- Comparison
- Transitional pain service vs standard of care
- Primary endpoint
- Quality of recovery (QoR-15 questionnaire)
- Follow-up
- Third postoperative day
Methodological detailssingle-centre, pragmatic, superiority, stratified for sex
- Single-centre
- Pragmatic
- Superiority
- Stratified for sex
Primary result
As reported in the abstract
QoR-15
- No difference between groups in QoR-15 on the third postoperative day (mean difference 2.0, 95% CI −5.5 to 9.4)
- p = 0.607
Secondary outcomes
| Outcome | TPS | SOC |
|---|---|---|
| Reduction in total daily oral MME vs baseline (chronic opioid users) · 3 months | median −30 (IQR −60–0) MME | median 0 (IQR −56–0) MME |
| Reduction in total daily oral MME vs baseline (chronic opioid users) · 6 months | median - 29.3 (IQR −65.6–0) MME | median 0 (IQR −60–7.5) MME |
Original publication
The effectiveness of a transitional pain service in patients undergoing surgery with an increased risk of developing chronic postsurgical pain (TRUSt study). A randomized clinical trial. J Clin Anesth. Published 16 September 2023. doi:10.
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