Airway management

Effects of avoidance versus use of neuromuscular blocking agents for facilitation of tracheal intubation in children and infants: a protocol for a systematic review, meta‐analysis and trial sequential analysis

Acta Anaesthesiol ScandPublished Protocol for a systematic review, meta-analysis and trial sequential analysis of randomised trials

Study context

Population
Pediatric participants (<18 years) undergoing tracheal intubation (oral or nasal) by direct or video laryngoscopy
Planned comparison
Avoidance vs use of neuromuscular blocking agents (NMBA) for facilitation of tracheal intubation
Primary endpoint
Incidence of difficult tracheal intubation
Methodological detailsPRISMA-P, Cochrane risk of bias tool (2011), grading of recommendations assessment, development, and evaluation (GRADE), Secondary outcomes: serious adverse events, failed intubation, upper airway discomfort or injury, difficult laryngoscopy
  • PRISMA-P
  • Cochrane risk of bias tool (2011)
  • GRADE
  • Secondary outcomes: serious adverse events, failed intubation, upper airway discomfort or injury, difficult laryngoscopy

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Effects of avoidance versus use of neuromuscular blocking agents for facilitation of tracheal intubation in children and infants: a protocol for a systematic review, meta‐analysis and trial sequential analysis. Acta Anaesthesiol Scand. Published 30 April 2024. doi:10.1111/aas.14429

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