ICU sedation, delirium & recovery
Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial
Authors' conclusion
The Caregiver Pathway has the potential to reduce the symptoms of PICS-F, especially among family caregivers whose patient has survived.
Study context
- Population
- Family caregivers to critically ill patients
- Participants
- 196 participants
- Comparison
- The Caregiver Pathway intervention vs control
- Interventionn = 101
- Controln = 95reference
Methodological detailssingle-centre, non-blinded
- Single-centre
- Non-blinded
Primary result
As reported in the abstract
Symptoms of post-traumatic stress disorder (PTSD) (IES-R score) · 6 months
Intervention
25.8
mean · 95% CI 21.9–29.7
Control
30.9
mean · 95% CI 26.7–35.0
P = 0.009
Further findings
| Outcome | Intervention | Control | P value |
|---|---|---|---|
| Symptoms of PTSD (IES-R score) · 12 monthsTrend toward an effect | 25.0 (95% CI 21.3–28.7) | 28.4 (95% CI 24.1–32.7) | P = 0.057 |
| PTSD (IES-R score), caregivers of surviving patients (subgroup) · 12 months | 19.8 (95% CI 15.3–24.2) | 29.1 (95% CI 23.5–34.6) | P = 0.001 |
| Anxiety (HADS-A score), caregivers of surviving patients (subgroup) · 12 months | 4.3 (95% CI 3.1–5.4) | 6.8 (95% CI 5.2–8.4) | P = 0.003 |
Original publication
Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial. Intensive Care Med. Published 6 October 2025. doi:10. 1007/ s00134-025-08139-x
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