ICU sedation, delirium & recovery

Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial

Intensive Care MedPublished Randomised controlled trial

Authors' conclusion

The Caregiver Pathway has the potential to reduce the symptoms of PICS-F, especially among family caregivers whose patient has survived.

Study context

Population
Family caregivers to critically ill patients
Participants
196 participants
Comparison
The Caregiver Pathway intervention vs control
  • Interventionn = 101
  • Controln = 95reference
Methodological detailssingle-centre, non-blinded
  • Single-centre
  • Non-blinded

Primary result

As reported in the abstract

Symptoms of post-traumatic stress disorder (PTSD) (IES-R score) · 6 months

Intervention

25.8

mean · 95% CI 21.9–29.7

Control

30.9

mean · 95% CI 26.7–35.0

P = 0.009

Further findings

OutcomeInterventionControlP value
Symptoms of PTSD (IES-R score) · 12 monthsTrend toward an effect25.0 (95% CI 21.3–28.7)28.4 (95% CI 24.1–32.7)P = 0.057
PTSD (IES-R score), caregivers of surviving patients (subgroup) · 12 months19.8 (95% CI 15.3–24.2)29.1 (95% CI 23.5–34.6)P = 0.001
Anxiety (HADS-A score), caregivers of surviving patients (subgroup) · 12 months4.3 (95% CI 3.1–5.4)6.8 (95% CI 5.2–8.4)P = 0.003

Original publication

Effects of The Caregiver Pathway intervention on symptoms of post-intensive care syndrome among family caregivers to critically ill patients: long-term results from a randomized controlled trial. Intensive Care Med. Published 6 October 2025. doi:10.1007/s00134-025-08139-x

Composed by AI from the published abstract and checked against it. How Briefs are made →

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