Emotional and psychosocial function after dorsal column spinal cord stimulator implantation: a systematic review and meta-analysis
Authors' conclusion
The results highlight the statistically and clinically significant improvements in emotional and psychosocial outcomes in patients with chronic pain undergoing SCS therapy.
Study context
- Population
- Patients who underwent spinal cord stimulation (SCS) implantation for chronic pain32 studies
- Comparison
- Emotional and psychosocial function after SCS implantation
- Outcome
- Pooled MD in anxiety, depression, global functioning, mental well-being and pain catastrophizing
- Follow-up
- 12 months
Methodological detailsGrading of Recommendation, Assessment, Development, and Evaluation (GRADE) certainty assessment, subgroup analyses
- GRADE certainty assessment
- Subgroup analyses
Pooled result
As reported in the abstract
Pooled MD in emotional and psychosocial outcomes after SCS
MD (95% CI)P value
Anxiety
−2.16(−2.84 to −1.49)
P < 0.001Depression
−4.66(−6.26 to −3.06)
P < 0.001Global functioning
20.30(14.69–25.90)
P < 0.001Mental well-being
4.95(3.60–6.31)
P < 0.001Pain catastrophizing
−12.09(−14.94 to −9.23)
P < 0.001Further pooled results
Subgroup analyses (study design, waveform paradigm)
- Differences in Global Assessment of Functioning and mental well-being by study design, and in depression by waveform paradigm
Original publication
Emotional and psychosocial function after dorsal column spinal cord stimulator implantation: a systematic review and meta-analysis. Reg Anesth Pain Med. Published 27 June 2024. doi:10.
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