Pain medicine

Evaluating the balance of benefits and harms in chronic pain clinical trials: prioritizing individual participants over individual outcomes

Reg Anesth Pain MedPublished Methodological review of randomised controlled trials

Authors' conclusion

Composite outcomes of benefits and harms are underutilized in chronic pain RCTs.

Study context

Population
Chronic pain randomized clinical trials (RCTs) published in 6 major pain journals, 2016–2021
Participants
73 RCTs
Primary endpoint
Inclusion of a composite outcome:
  • Measure of benefits
  • Harms

Primary result

As reported in the abstract

RCTs including a composite outcome:
  • Measure of benefits
  • Harms
RCTs with a composite outcome of benefits and harms (of 73)
2

Original publication

Evaluating the balance of benefits and harms in chronic pain clinical trials: prioritizing individual participants over individual outcomes. Reg Anesth Pain Med. Published 14 November 2023. doi:10.1136/rapm-2023-104809

Composed by AI from the published abstract and checked against it. How Briefs are made →

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