Evaluation of bromocriptine for the reduction of fever in patients with acute neurologic injury: A retrospective cohort study
Authors' conclusion
This study found that bromocriptine 5 mg every 8 h is safe when used in combination with acetaminophen for fever management among patients with neurologic injury.
Study context
- Population
- Neuro ICU patients with acute neurologic injury treated for fever
- Participants
- 67 patients
- Exposure
- BROMO vs APAP
- BROMOn = 28
- APAPn = 39reference
- Outcome
- Reduction of temperature (°C)
- Follow-up
- 72 h after initiation
Main finding
As reported in the abstract
72 h
BROMO
−0.86
°C
APAP
−0.39
°C
P = 0.017
Observational data: associations, not effects.
Safety
- No adverse effects in either group
Original publication
Evaluation of bromocriptine for the reduction of fever in patients with acute neurologic injury: A retrospective cohort study. J Crit Care. Published 27 September 2025. doi:10.
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