Perioperative medicine & outcomes

Excess mortality among non-COVID-19 surgical patients attributable to the exposure of French intensive and intermediate care units to the pandemic

Intensive Care MedPublished Nationwide observational cohort study

Authors' conclusion

Significant excess mortality essentially occurred outside of the ICU/IMCU, suggesting that access of surgical patients to critical care was limited.

Study context

Population
All patients without COVID-19 who underwent surgery in France, 01/01/2019 to 31/12/2020
Participants
1,870,515 patients · 655 hospitals
Exposure
Surgery in hospitals highly exposed to the COVID-19 pandemic (ICU/IMCU occupancy by COVID-19 patients) vs low-or-no exposure, 2020 vs 2019
Outcome
Standardized in-hospital mortality (inside or outside the ICU/IMCU)
Methodological detailsmultilevel models, triple-difference analysis
  • Multilevel models
  • Triple-difference analysis

Main finding

As reported in the abstract

In-hospital mortality, first semester 2020 · first semester of 2020

Adjusted ratio of ORs

1.56

95% CI 1.34–1.81

triple-difference

Adjusted ratio of ORs

1.27

95% CI 1.02–1.58

deaths inside the ICU/IMCU

Adjusted ratio of ORs

1.98

95% CI 1.57–2.5

deaths outside the ICU/IMCU

Overall mortality
2%

Observational data: associations, not effects.

Further findings

OutcomeAdjusted ratio of ORs (CI)
Learning effect, second vs first semester · second semester of 2020Significant learning effect0.76 (0.58–0.99)

Standardized mortality increase vs 2019, highly exposed hospitals

First semester 2020: increase
1% (95% CI 0.6-1.4%)
Second semester 2020: increase 0.4% (0-1%)

Original publication

Excess mortality among non-COVID-19 surgical patients attributable to the exposure of French intensive and intermediate care units to the pandemic. Intensive Care Med. Published 25 February 2023. doi:10.1007/s00134-023-07000-3

Composed by AI from the published abstract and checked against it. How Briefs are made →

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