Perioperative medicine & outcomes

Extended-age Out-of-sample Validation of Risk Stratification Index 3.0 Models Using Commercial All-payer Claims

AnesthesiologyPublished Prognostic model external validation study

Authors' conclusion

Similar predictive performance in Medicare and in younger and healthier populations indicates that Risk Stratification Index 3.0 models are valid across a broad range of adult hospital admissions.

Study context

Population
Surgical and medical hospital admissions, younger and healthier 2017 Utah and Oregon state populations (All Payer Claims)
Comparison
Utah vs Oregon
Outcome
Performance of Risk Stratification Index 3.0 models (unplanned admissions, in-hospital mortality, AKI, sepsis, pneumonia, respiratory failure, major cardiac complications)
Methodological detailsout-of-sample validation, retrospective claims data
  • Out-of-sample validation
  • Retrospective claims data

Performance

As reported in the abstract

Test or modelAdmissionsPatientsCalibration R2Mean sensitivity, highest 5% risk
Utah55,10940,7100.93 (0.84 to 0.97)28% (17 to 44)
Oregon21,21316,9510.85 (0.71 to 0.91)37% (20 to 56)

Admissions

Utah55,109
Oregon21,213

Patients

Utah40,710
Oregon16,951

Calibration R2

Utah0.93 (0.84 to 0.97)
Oregon0.85 (0.71 to 0.91)

Mean sensitivity, highest 5% risk

Utah28% (17 to 44)
Oregon37% (20 to 56)
Average AUC across both state datasets
0.83 (0.71 to 0.91)

Original publication

Extended-age Out-of-sample Validation of Risk Stratification Index 3.0 Models Using Commercial All-payer Claims. Anesthesiology. Published 20 December 2022. doi:10.1097/aln.0000000000004477

Composed by AI from the published abstract and checked against it. How Briefs are made →

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