Cardiac arrest & resuscitation
External validation of the TiPS65 score for predicting good neurological outcomes in patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation
Authors' conclusion
The TiPS65 score shows reasonable discrimination and predictive performances.
Study context
- Population
- Adults with out-of-hospital cardiac arrest (OHCA) and shockable rhythm treated with extracorporeal cardiopulmonary resuscitation (ECPR), Japanese registry, 2018–201964 (10.8%) favourable outcome
- Participants
- 590 adults
- Comparison
- TiPS65 >1 vs TiPS65 >3
- Outcome
- Survival with favourable neurological outcome (Cerebral Performance Category 1 or 2)
- Follow-up
- 30 days
Methodological detailsmulticentre, nationwide, prospective registry
- Multicentre
- Nationwide
- Prospective registry
Performance
As reported in the abstract
Prediction of 30-day favourable neurological outcome
| Strategy | Sensitivity | Specificity |
|---|---|---|
| TiPS65 >1 | 0.906 (95%CI: 0.807-0.965) | 0.430 (95%CI: 0.387-0.473) |
| TiPS65 >3 | 0.172 (95%CI: 0.089-0.287) | 0.971 (95%CI: 0.953-0.984) |
Sensitivity
TiPS65 >10.906 (95%CI: 0.807-0.965)
TiPS65 >30.172 (95%CI: 0.089-0.287)
Specificity
TiPS65 >10.430 (95%CI: 0.387-0.473)
TiPS65 >30.971 (95%CI: 0.953-0.984)
- C-statistic of TiPS65 score
- 0.729 (95% CI 0.672-0.786)
Original publication
External validation of the TiPS65 score for predicting good neurological outcomes in patients with out-of-hospital cardiac arrest treated with extracorporeal cardiopulmonary resuscitation. Resuscitation. Published 25 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →