Pediatric anesthesia & critical care
First documented rhythm and clinical outcome in children who undergo extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest: A report from the american heart association get with the guidelines® – resuscitation registry (GWTG-R)
Main finding · Survival to hospital dischargeResult — go to the resultRelative risk 1.2 95% CI 0.95–1.53Authors' conclusion
In children with in-hospital cardiac arrest undergoing ECPR, there was no significant difference in survival or favorable neurologic outcome between those with initial shockable rhythm compared to non-shockable rhythm.
Study context
- Population
- Children <18 years with in-hospital extracorporeal cardiopulmonary resuscitation (ECPR) events ≥10 minutes, AHA GWTG-R registry, 2014–2019287 matched
- Participants
- 466 children
- Exposure
- Initial shockable vs non-shockable rhythm in pediatric ECPR
- Shockablen = 82
- Non-shockablen = 384reference
- Outcome
- Survival to hospital discharge
Methodological detailspropensity-score matched, registry (GWTG-R)
- Propensity-score matched
- Registry (GWTG-R)
Main finding
As reported in the abstract
Relative risk
1.2
95% CI 0.95–1.53
P = 0.13
Shockable vs Non-shockable
RR 1.2 (95% CI 0.95–1.53); P = 0.13
Observational data: associations, not effects.
Further findings
| Outcome | RR (95% CI) | P value | |
|---|---|---|---|
| Favorable neurologic outcome (PCPC 1 or 2, or no decline from baseline)Matched cohort | 1.28 (0.84–1.96) | P = 0.25 | |
| 0.512Relative risk (log scale) |
Original publication
First documented rhythm and clinical outcome in children who undergo extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest: A report from the american heart association get with the guidelines® – resuscitation registry (GWTG-R). Resuscitation. Published 8 November 2023. doi:10.
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