ICU sedation, delirium & recovery
A Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU
Methodological detailsfocused update, GRADE approach, systematic review for each PICO question, evidence-to-decision framework, Interprofessional task force of 24 individuals including ICU survivors
- Focused update
- GRADE approach
- Systematic review for each PICO question
- Evidence-to-decision framework
- Interprofessional task force of 24 individuals including ICU survivors
Recommendations
As issued by the authors
- conditional
Use dexmedetomidine over propofol for sedation
- conditional
Provide enhanced mobilization/rehabilitation over usual mobilization/rehabilitation
- conditional
Administer melatonin
Unable to issue a recommendation on benzodiazepines to treat anxiety
Unable to issue a recommendation on antipsychotics to treat delirium
Original publication
A Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU. Crit Care Med. Published 21 February 2025. doi:10.
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