From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU
Recommendations
As issued by the authors
Identification of subpopulations must differentiate response to treatment, not only prognosis, ideally by defining endotypes
A precision medicine approach must be evaluated in prospective clinical studies requiring novel adaptive trial designs
Subpopulations must be readily identifiable and applicable to all critically ill populations around the world
Global collaboration of investigators, clinicians, industry, and patients over many years will be required
Original publication
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. Am J Respir Crit Care Med. Published 15 July 2024. doi:10.
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