Cardiac arrest & resuscitation
Gender Disparity in Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest
Primary resultResult — go to the resultOdds ratio 1.68 95% CI 1.46–1.93Authors' conclusion
ECPR was significantly more frequently performed in male patients with OHCA. Subgroup analyses suggest that gender disparity is particularly evident in cases where indications for ECPR are not clearly defined.
Study context
- Population
- Adults (≥ 18 yr) with out-of-hospital cardiac arrest (OHCA) from nonexternal causes, no ROSC before or upon hospital arrival, transported within 60 min of emergency call to facilities with 24-hour extracorporeal cardiopulmonary resuscitation (ECPR) availability; Japanese Association for Acute Medicine Out-of-Hospital Cardiac Arrest (JAAM-OHCA) Registry, 164 hospitals in Japan, June 2014–December 2022median age 78.0 years
- Participants
- 47,965 adults
- Comparison
- Male vs female sex
- Malen = 28,754
- Femalen = 19,211reference
- Primary endpoint
- Receiving ECPR (emergent venoarterial ECMO before ROSC within 60 min after hospital arrival)
Methodological detailsobservational cohort study, multicentre, multilevel logistic regression
- Observational cohort study
- Multicentre
- Multilevel logistic regression
Primary result
As reported in the abstract
Odds ratio
1.68
95% CI 1.46–1.93
Events by treatment group
Male vs Female
OR 1.68 (95% CI 1.46–1.93)
Further findings
- Male predominance consistent across most subgroups but not observed in patients unequivocally eligible or ineligible for ECPR
Original publication
Gender Disparity in Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest. Crit Care Med. Published 13 January 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →