General anaesthesia for caesarean delivery in women with class 3 obesity: case series from nine hospitals across the north-west of England (2022–2023)
Authors' conclusion
Our study highlights variability in the administration of general anaesthesia for caesarean delivery in women with class 3 obesity, and frequent occurrence of hypoxia.
Study context
- Population
- Pregnant women with class 3 obesity undergoing GA for elective and non-elective caesarean delivery, 9 maternity units, north-west England, 2022–20239 maternity units
- Participants
- 56 women
- Outcome
- Conduct of GA for caesarean delivery: preoxygenation technique, anaesthetic agents, hypoxia (SpO2 ≤ 94%), difficult intubation
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
- De novo facemask preoxygenation
- 82%
- HFNO preoxygenation
- 13.2%
- Propofol used
- 78%
- Opioid predelivery
- 55%
- Rocuronium as NMBA for intubation
- 68%
- Video laryngoscopy
- 68%
- Hypoxia (SpO2 ≤ 94%) documented
- 25%
- Difficult intubation, 1 woman
- 1.8% (95% CI 0.0-9.6)
Observational data: associations, not effects.
Original publication
General anaesthesia for caesarean delivery in women with class 3 obesity: case series from nine hospitals across the north-west of England (2022–2023). Int J Obstet Anesth. Published 23 October 2025. doi:10. 1016/ j. ijoa. 2025. 104806
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