Obstetric anesthesia

General anaesthesia for caesarean delivery in women with class 3 obesity: case series from nine hospitals across the north-west of England (2022–2023)

Int J Obstet AnesthPublished Retrospective case series

Authors' conclusion

Our study highlights variability in the administration of general anaesthesia for caesarean delivery in women with class 3 obesity, and frequent occurrence of hypoxia.

Study context

Population
Pregnant women with class 3 obesity undergoing GA for elective and non-elective caesarean delivery, 9 maternity units, north-west England, 2022–20239 maternity units
Participants
56 women
Outcome
Conduct of GA for caesarean delivery: preoxygenation technique, anaesthetic agents, hypoxia (SpO2 ≤ 94%), difficult intubation
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

De novo facemask preoxygenation
82%
HFNO preoxygenation
13.2%
Propofol used
78%
Opioid predelivery
55%
Rocuronium as NMBA for intubation
68%
Video laryngoscopy
68%
Hypoxia (SpO2 ≤ 94%) documented
25%
Difficult intubation, 1 woman
1.8% (95% CI 0.0-9.6)

Observational data: associations, not effects.

Original publication

General anaesthesia for caesarean delivery in women with class 3 obesity: case series from nine hospitals across the north-west of England (2022–2023). Int J Obstet Anesth. Published 23 October 2025. doi:10.1016/j.ijoa.2025.104806

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