Global usage of spinal cord stimulation therapy for chronic pain syndromes: a systematic review and meta-analysis
Authors' conclusion
Significant associations exist between geographic regions and patient demographics in SCS research, with notable disparities in research concentration
Study context
- Population
- Adults (≥18 years) with chronic pain lasting ≥3 months treated with spinal cord stimulation (SCS), studies from 2000 onward187 studies
- Outcome
- Associations between geographic regions and patient age demographics in SCS research
Methodological detailsPRISMA guidelines, Five major databases searched through October 2024; randomised trials, comparative studies and case series with ≥10 patients included
- PRISMA guidelines
- Five major databases searched through October 2024; randomised trials, comparative studies and case series with ≥10 patients included
Pooled result
As reported in the abstract
Age distribution across geographic regions
- Heterogeneity in age distributions across regions: Asian studies higher mean ages vs North America; European studies lower mean ages
Further pooled results
Industry funding of studies
- Studies receiving industry funding
- 57%
- Significant associations between funding source and geographic origin; research concentrated in high-income regions
Most prevalent condition globally
- Post-surgical pain syndrome-thoracolumbar, share of cases
- 44.9%
Original publication
Global usage of spinal cord stimulation therapy for chronic pain syndromes: a systematic review and meta-analysis. Reg Anesth Pain Med. Published 31 August 2025. doi:10.
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