Safety, quality & education

Health‐related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study

Acta Anaesthesiol ScandPublished Protocol for a Monte Carlo simulation study

Study context

Population
Simulated broad critical care population eligible for inclusion in a large pragmatic trial15,360 simulated scenarios
Planned comparison
Areas under the health-related quality of life (HRQoL) trajectories vs single-sampled HRQoL at the end of follow-up
Methodological detailsfull factorial design, simulated two-arm trials with 1:1 randomisation, 7 simulation parameters; 100,000 two-arm trials per scenario; HRQoL sampled fortnightly after intensive care unit (ICU) discharge
  • Full factorial design
  • Simulated two-arm trials with 1:1 randomisation
  • 7 simulation parameters; 100,000 two-arm trials per scenario; HRQoL sampled fortnightly after ICU discharge

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Health‐related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study. Acta Anaesthesiol Scand. Published 31 August 2023. doi:10.1111/aas.14324

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