Health‐related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study
Study context
- Population
- Simulated broad critical care population eligible for inclusion in a large pragmatic trial15,360 simulated scenarios
- Planned comparison
- Areas under the health-related quality of life (HRQoL) trajectories vs single-sampled HRQoL at the end of follow-up
Methodological detailsfull factorial design, simulated two-arm trials with 1:1 randomisation, 7 simulation parameters; 100,000 two-arm trials per scenario; HRQoL sampled fortnightly after intensive care unit (ICU) discharge
- Full factorial design
- Simulated two-arm trials with 1:1 randomisation
- 7 simulation parameters; 100,000 two-arm trials per scenario; HRQoL sampled fortnightly after ICU discharge
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Health‐related quality of life trajectories in critical illness: Protocol for a Monte Carlo simulation study. Acta Anaesthesiol Scand. Published 31 August 2023. doi:10. 1111/ aas. 14324
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