ICU sedation, delirium & recovery
Health status and quality of life before critical illness: Northern Finland Birth Cohort 1966 study
Authors' conclusion
In this study examining previously un-hospitalized patients, the main factors associated with future critical illness were neurological comorbidities, malignancy, alcohol misuse, smoking, low maximum muscle strength, and less frequent physical exercise compared with those with hospitalization not requiring ICU admission.
Study context
- Population
- NFBC1966 participants not hospitalized for any reason before the follow-up visit at age 31met inclusion criteria
- Participants
- 849 participants
- Exposure
- Intensive care unit (ICU) admission vs regular hospital ward treatment
- ICUn = 69
- Controlsn = 780reference
- Outcome
- Health-related factors at age 31 associated with later critical illness
Methodological detailsbirth cohort (NFBC1966)
- Birth cohort (NFBC1966)
Main finding
As reported in the abstract
Health-related factors at age 31
- ICU
- Neurological diseases 26% vs. 16% (95% CI −21.8% to −0.2%)
- ICU
- Malignancy 3% vs. 0.7% (95% CI −9.7% to 0.0%)
- ICU
- Alcohol abuse 4.5% vs. 1% (95% CI −11.5% to −0.3%)
- ICU
- Smoking 77% vs. 65% (95% CI −21.6% to −0.3%)
- ICU
- Violent injuries 17% vs. 7% (95% CI −20.2% to −1.9%)
- ICU
- Hard physical activity 65% vs. 78% (95% CI 2.1%–25.3%)
- ICU
- Maximal hand grip strength 30 vs. 34 kg (95% CI −8.2 to 8.6)
Observational data: associations, not effects.
Original publication
Health status and quality of life before critical illness: Northern Finland Birth Cohort 1966 study. Acta Anaesthesiol Scand. Published 28 June 2024. doi:10.
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