Pain medicine

Hidden risk of gadolinium-based contrast agents during interventional pain medicine procedures: a retrospective chart review

Reg Anesth Pain MedPublished Retrospective chart review

Authors' conclusion

The current study raises concern regarding the use of gadolinium-based contrast media in axial spine procedures, with the risk of potential severe adverse events, without evidence-based need for avoiding iodinated contrast media.

Study context

Population
Patients who received gadolinium-based contrast media during fluoroscopically guided axial spine procedures (epidural steroid injections, epidural blood patches, selective nerve root blocks), January 1, 2019 to May 1, 2022
Participants
508 patients · 697 epidural procedures
Outcome
Adverse events consistent with possible, probable, or clear intrathecal gadolinium exposure
Follow-up
Within 1 month of the procedure
Methodological detailsdescriptive, Saved fluoroscopy images reviewed where gadolinium-related side effect suspected
  • Descriptive
  • Saved fluoroscopy images reviewed where gadolinium-related side effect suspected

Main finding

As reported in the abstract

Adverse event possibly, probably or clearly consistent with intrathecal gadolinium exposure · within 1 month

Patients with adverse event

23

Calculated adverse event rate

3.3%

Observational data: associations, not effects.

Safety

Adverse events requiring additional medical evaluation or treatment

Patients requiring additional medical evaluation or treatment
10

Original publication

Hidden risk of gadolinium-based contrast agents during interventional pain medicine procedures: a retrospective chart review. Reg Anesth Pain Med. Published 11 November 2023. doi:10.1136/rapm-2023-104952

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