Hidden risk of gadolinium-based contrast agents during interventional pain medicine procedures: a retrospective chart review
Authors' conclusion
The current study raises concern regarding the use of gadolinium-based contrast media in axial spine procedures, with the risk of potential severe adverse events, without evidence-based need for avoiding iodinated contrast media.
Study context
- Population
- Patients who received gadolinium-based contrast media during fluoroscopically guided axial spine procedures (epidural steroid injections, epidural blood patches, selective nerve root blocks), January 1, 2019 to May 1, 2022
- Participants
- 508 patients · 697 epidural procedures
- Outcome
- Adverse events consistent with possible, probable, or clear intrathecal gadolinium exposure
- Follow-up
- Within 1 month of the procedure
Methodological detailsdescriptive, Saved fluoroscopy images reviewed where gadolinium-related side effect suspected
- Descriptive
- Saved fluoroscopy images reviewed where gadolinium-related side effect suspected
Main finding
As reported in the abstract
Adverse event possibly, probably or clearly consistent with intrathecal gadolinium exposure · within 1 month
Patients with adverse event
23
Calculated adverse event rate
3.3%
Observational data: associations, not effects.
Safety
Adverse events requiring additional medical evaluation or treatment
- Patients requiring additional medical evaluation or treatment
- 10
Original publication
Hidden risk of gadolinium-based contrast agents during interventional pain medicine procedures: a retrospective chart review. Reg Anesth Pain Med. Published 11 November 2023. doi:10. 1136/ rapm-2023-104952
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