Cardiac arrest & resuscitation
In-hospital cardiac arrest in non-ST-segment elevation myocardial infarction: characteristics and association of early intervention with risk-findings from the CCC-ACS project
Authors' conclusion
IHCA remains a fatal complication of NSTEMI, often occurring early after admission.
Study context
- Population
- Patients diagnosed with NSTEMI in the CCC-ACS project, China, November 2014 to December 202029.45% female
- Participants
- 32,094 patients
- Exposure
- NSTEMI patients with vs without in-hospital cardiac arrest (IHCA)
- Outcome
- IHCA incidence among NSTEMI patients and in-hospital mortality of IHCA patients
Methodological detailsnationwide registry, Cox proportional hazards models
- Nationwide registry
- Cox proportional hazards models
Main finding
As reported in the abstract
IHCA incidence
IHCA incidence
397
1.24%
IHCA incidence in 2014
2.06%
IHCA incidence in 2020
0.89%
In-hospital mortality of IHCA patients
65.74%
Observational data: associations, not effects.
Further findings
Timing of IHCA
- IHCA on day of admission
- 25.59%
- Median time to IHCA (days)
- 4 [1-7]
Risk and protective factors for IHCA
- Risk factors: prior OHCA, ≥100-fold elevated TnT/TnI, age ≥75 years, Killip class IV, SBP <90 mmHg and heart rate >100 bpm at admission, history of HF, renal failure, ischemic stroke, latest glucose >10 mmol/L
- Coronary angiography before IHCA was the strongest protective factor
Original publication
In-hospital cardiac arrest in non-ST-segment elevation myocardial infarction: characteristics and association of early intervention with risk-findings from the CCC-ACS project. Resuscitation. Published 17 March 2026. doi:10. 1016/ j. resuscitation. 2026. 111064
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