How Long Should Patients Be Treated With Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation? Individual Patient Data Pooled Analysis
Authors' conclusion
The present study demonstrated that prolonged venoarterial ECMO support after adult cardiac surgery may be justified.
Study context
- Population
- Adults with cardiogenic shock refractory to medical therapies after cardiac surgery treated with venoarterial extracorporeal membrane oxygenation (ECMO)
- Participants
- 1,267 adults · 10 studies · 25 hospitals
- Comparison
- Duration of postcardiotomy venoarterial ECMO
- Outcome
- In-hospital mortality
Methodological detailsmultilevel mixed-effects logistic regression, adjusted for patient risk profile and operative variables
- Multilevel mixed-effects logistic regression
- Adjusted for patient risk profile and operative variables
Pooled result
As reported in the abstract
In-hospital mortality by ECMO duration
- In-hospital mortality lowest with 3-6 days of venoarterial ECMO
- Risk of in-hospital mortality not significantly increased with >6 days up to 20 days
- Adjusted for cluster effect of hospitals, patient risk profile and operative variables
Original publication
How Long Should Patients Be Treated With Postcardiotomy Venoarterial Extracorporeal Membrane Oxygenation? Individual Patient Data Pooled Analysis. Crit Care Med. Published 18 February 2025. doi:10.
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