Impact of Covid-19 on risk of severe maternal morbidity
Main finding · Severe maternal morbidityResult — go to the resultRelative risk 2.02 95% CI 1.76–2.31Authors' conclusion
Covid-19 infection during pregnancy increases risk of life-threatening maternal morbidity, including renal, embolic, and hemorrhagic complications.
Study context
- Population
- Pregnancies in Quebec, Canada, March 2020–March 2022
- Participants
- 162,576 pregnancies
- Exposure
- Covid-19 infection vs no infection
- Outcome
- Severe maternal morbidity
- Follow-up
- During pregnancy up to 42 days postpartum
Methodological detailsadjusted log-binomial regression
- Adjusted log-binomial regression
Main finding
As reported in the abstract
Relative risk
2.02
95% CI 1.76–2.31
Covid-19 infection vs No infection
RR 2.02 (95% CI 1.76–2.31)
Observational data: associations, not effects.
Further findings
Acute renal failure
- Covid-19 infection vs no infection, RR
- 3.01 (1.79-5.06) (95% CI)
- Adjusted log-binomial regression
Embolism, shock, sepsis and disseminated intravascular coagulation
- Covid-19 infection vs no infection, RR
- 1.35 (0.95-1.93) (95% CI)
- Adjusted log-binomial regression
Severe hemorrhage
- Covid-19 infection vs no infection, RR
- 1.49 (1.09-2.04) (95% CI)
- Adjusted log-binomial regression
Severe maternal morbidity by infection severity and period (subgroup)
- Severe antepartum infection, RR
- 13.60 (10.72-17.26) (95% CI)
- Severe peripartum infection, RR
- 20.93 (17.11-25.60) (95% CI)
- Mild antepartum infection, RR
- 3.43 (2.42-4.86) (95% CI)
Severe maternal morbidity by circulating variant (subgroup)
- Risk around 3 times greater during wildtype, alpha and delta circulation
- Risk only 1.2 times greater during omicron
Original publication
Impact of Covid-19 on risk of severe maternal morbidity. Crit Care. Published 5 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →