Pediatric anesthesia & critical care
Impact of intravenous dexamethasone on the initiation and recovery of atracurium in children: A double‐blinded randomized controlled trial
Authors' conclusion
Application of a single bolus dose (0.15 mg/kg) of dexamethasone during induction does not attenuate atracurium-induced neuromuscular blockade in children.
Study context
- Population
- ASA I and II children aged 4–15 years undergoing elective surgery with atracurium
- Participants
- 100 participants
- Comparison
- IV dexamethasone 0.15 mg/kg vs 0.9% saline at induction
- Dexamethasonen = 50
- Salinen = 50reference
Methodological detailsdouble-blinded
- Double-blinded
Primary result
As reported in the abstract
Onset time and recovery index of atracurium
| Group | Value | Recovery index |
|---|---|---|
| Dexamethasone | 1.96 ± 0.39 | 8.04 ± 2.14 |
| Saline | 2.01 ± 0.51 | 8.9 ± 3.4 |
Value
Dexamethasone1.96 ± 0.39
Saline2.01 ± 0.51
Recovery index
Dexamethasone8.04 ± 2.14
Saline8.9 ± 3.4
Further findings
Clinical duration, recovery time, total recovery period
- Similar in the two groups
Original publication
Impact of intravenous dexamethasone on the initiation and recovery of atracurium in children: A double‐blinded randomized controlled trial. Paediatr Anaesth. Published 26 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →