Pediatric anesthesia & critical care
The impact of preoperative carbohydrate ingestion one hour before surgery on children's preoperative anxiety and postoperative pain under ultrasound monitoring: A randomized controlled trial
Authors' conclusion
Oral intake of 5 ml/kg of carbohydrates 1 h before surgery is safe, it can significantly improve preoperative anxiety and blood glucose fluctuations in children and reduce the incidence of perioperative adverse reactions, but it does not significantly improve postoperative pain.
Study context
- Population
- Children with obstructive sleep apnea hypopnea syndrome (OSAHS) undergoing adenotonsillectomy, single hospital in China, June–August 2024
- Comparison
- E vs C
- Primary endpoint
- Preoperative anxiety and postoperative pain
Primary result
As reported in the abstract
Preoperative anxiety (Modified Yale Preoperative Anxiety Scale) and postoperative pain (Wong-Baker FACES)
- Preoperative anxiety significantly lower in E vs C
- P < 0.05
- No significant difference in postoperative pain scores between groups
- P > 0.05
Further findings
Gastric antrum CSA and gastric volume (GV) (ultrasound) · after ingesting carbohydrates
- CSA and GV significantly higher in E vs C
- P < 0.05
- No significant gastric content in either group before entering the operating room
- P > 0.05
Fasting blood glucose, blood insulin, insulin resistance index · perioperative
- All significantly lower in E vs C
- P < 0.05
Safety
- Incidence of PONV and agitation significantly lower in E vs C
- P < 0.05
Original publication
The impact of preoperative carbohydrate ingestion one hour before surgery on children's preoperative anxiety and postoperative pain under ultrasound monitoring: A randomized controlled trial. J Clin Anesth. Published 10 October 2025. doi:10. 1016/ j. jclinane. 2025. 112031
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