ICU sedation, delirium & recovery
Implementation and evaluation of the multidisciplinary “ABCDEF of sleep” protocol in Brazilian intensive care units: A quasi-experimental study. Results of a two-phase
An erratum to this article was published (J Crit Care, 8 Sep 2026 ↗)
Authors' conclusion
A pragmatic sleep protocol improved subjective sleep quality and reduced environmental disturbances in ICU patients, but did not impact major clinical outcomes.
Study context
- Population
- Adult patients with ICU stay of ≥2 nights, two Brazilian intensive care units (ICUs), 2022–2024
- Participants
- 112 patients
- Comparison
- Intervention vs Control
- Interventionn = 51
- Controln = 61reference
- Outcome
- Global RCSQ score (aggregated 3-night)
Methodological detailsmulticentre, two-phase
- Multicentre
- Two-phase
Main finding
As reported in the abstract
- Intervention vs Control: P = 0.31
Secondary outcomes
| Outcome | P value |
|---|---|
| RCSQ score, second night (per-night analysis)Higher in intervention group | P = 0.008 |
| Perceived sleep quality and environmental disturbances | P ≤ 0.001 |
- Perceived sleep quality and environmental disturbances: improved perceived sleep quality and reduced environmental disturbances
Richards-Campbell Sleep Questionnaire (RCSQ) score, second night (per-night analysis)
- No differences on nights 1 or 3
Mortality, mechanical ventilation, LOS
- No effects of the intervention
Family-reported sleep perception
- Did not differ between groups
Original publication
Implementation and evaluation of the multidisciplinary “ABCDEF of sleep” protocol in Brazilian intensive care units: A quasi-experimental study. Results of a two-phase. J Crit Care. Published 12 June 2026. doi:10.
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