ICU sedation, delirium & recovery
Improved survival in patients admitted to ICU with multiple myeloma: a retrospective cohort analysis
Main finding · Adjusted mortalityResult — go to the resultEstimate 0.68 CI 0.49–0.95Authors' conclusion
Survival in MM patients admitted to ICU improved in the recent years.
Study context
- Population
- Patients with multiple myeloma admitted to ICU
- Participants
- 199 vs 229
- Exposure
- ICU admission in recent period vs first period
- 2007-2015n = 199reference
- 2016-2023n = 229
- Outcome
- Short- and long-term mortality
Methodological detailssingle-centre, multivariate analysis
- Single-centre
- Multivariate analysis
Main finding
Adjusted mortality
Estimate
0.68
CI 0.49–0.95
P = 0.02
As reported in the abstract
Observational data: associations, not effects.
Further findings
ICU and one-year mortality (all patients)
- ICU mortality
- 12.1% (n = 50)
- One-year mortality
- 40.6% (n = 170)
Reason for ICU admission
- Shock, second vs first period
- 29.7% vs 13.7%
- Acute respiratory failure, first vs second period (as printed)
- 35.2% vs 46.7%
- Difference between periods
- P < 0.001
ICU organ support and stay (all patients)
- Invasive mechanical ventilation
- 115 (26.9%)
- Vasopressors
- 105 (24.5%)
- RRT
- 97 (22.7%)
- Median ICU LOS, days
- 3 (2-6)
- SOFA score Day 1
- 5 (2-7)
Original publication
Improved survival in patients admitted to ICU with multiple myeloma: a retrospective cohort analysis. Ann Intensive Care. Published 13 June 2026. doi:10. 1016/ j. aicoj. 2026. 100100
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