ICU sedation, delirium & recovery

Improved survival in patients admitted to ICU with multiple myeloma: a retrospective cohort analysis

Ann Intensive CarePublished Retrospective cohort study

Main finding · Adjusted mortalityResult — go to the resultEstimate 0.68 CI 0.49–0.95

Authors' conclusion

Survival in MM patients admitted to ICU improved in the recent years.

Study context

Population
Patients with multiple myeloma admitted to ICU
Participants
199 vs 229
Exposure
ICU admission in recent period vs first period
  • 2007-2015n = 199reference
  • 2016-2023n = 229
Outcome
Short- and long-term mortality
Methodological detailssingle-centre, multivariate analysis
  • Single-centre
  • Multivariate analysis

Main finding

Adjusted mortality

Estimate

0.68

CI 0.49–0.95

P = 0.02

As reported in the abstract

Observational data: associations, not effects.

Further findings

ICU and one-year mortality (all patients)

ICU mortality
12.1% (n = 50)
One-year mortality
40.6% (n = 170)

Reason for ICU admission

Shock, second vs first period
29.7% vs 13.7%
Acute respiratory failure, first vs second period (as printed)
35.2% vs 46.7%
Difference between periods
P < 0.001

ICU organ support and stay (all patients)

Invasive mechanical ventilation
115 (26.9%)
Vasopressors
105 (24.5%)
RRT
97 (22.7%)
Median ICU LOS, days
3 (2-6)
SOFA score Day 1
5 (2-7)

Original publication

Improved survival in patients admitted to ICU with multiple myeloma: a retrospective cohort analysis. Ann Intensive Care. Published 13 June 2026. doi:10.1016/j.aicoj.2026.100100

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