Perioperative medicine & outcomes
In search of a characterisation of frailty: applying exploratory factor analysis to ageing preoperative patients : Cross-sectional study
Authors' conclusion
In our quest to characterise frailty, we found that this is best described by an aggregate of reductions in physical activity, impairment in cognitive status and anaemia, while comorbidities are not associated with it.
Study context
- Population
- Preoperative patients aged 65 years or older60% men
- Participants
- 109 patients
- Exposure
- Factors from exploratory factor analysis (EFA) of 8 frailty scales vs frailty by Clinical Frailty Scale (CFS)
- Outcome
- Association of EFA factors with frailty according to the CFS (≥ 4 points)
Methodological detailsexploratory factor analysis, concordance study
- Exploratory factor analysis
- Concordance study
Main finding
As reported in the abstract
Association with frailty (CFS ≥ 4)
Estimate (95% CI)
F2strong association
adjusted OR 3.65(1.57–8.53)
F3milder relationship
OR 2.54(1.28–5.02)
F1no association
OR 1.15(0.58–2.26)
Observational data: associations, not effects.
Original publication
In search of a characterisation of frailty: applying exploratory factor analysis to ageing preoperative patients : Cross-sectional study. Perioper Med (Lond). Published 23 June 2025. doi:10.
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