Perioperative medicine & outcomes

The incidence of potentially serious complications during non‐obstetric anaesthetic practice in the United Kingdom: an analysis from the 7th National Audit Project ( NAP7 ) activity survey

AnaesthesiaPublished Prospective national cohort study

Authors' conclusion

These data represent the rates of potentially serious complications during routine anaesthesia care and may be valuable for risk assessment and patient consent.

Study context

Population
Unselected patients undergoing anaesthesia at UK hospital sites (Royal College of Anaesthetists 7th National Audit Project); obstetric cases excluded from further analysis20,996 non-obstetric cases analysed
Participants
24,172 patients
Outcome
Potentially serious complications during anaesthesia
Methodological detailsactivity survey, unselected patients, 4-day snapshot, national audit (NAP7), 352 of 416 (85%) invited hospital sites completed the survey, Anaesthetists recorded anonymous details of all cases over 4 days via online survey
  • Activity survey
  • Unselected patients
  • 4-day snapshot
  • National audit (NAP7)
  • 352 of 416 (85%) invited hospital sites completed the survey
  • Anaesthetists recorded anonymous details of all cases over 4 days via online survey

Main finding

As reported in the abstract

Potentially serious complications, non-obstetric cases
Cases with ≥1 complication
1150 (5%)
Complications reported
1705
Circulatory events
616, 36%
Airway events
418, 25%
Metabolic events
264, 15%
Breathing events
259, 15%
Neurological events
41, 2%
Single complication
851 (4%)
Two complications
166 (1%)
Three or more complications
133 (1%)

Observational data: associations, not effects.

Further findings

All cases incl. obstetric

Discrete potentially serious complications
1922
Cases with complications
1337 (6%)
Obstetric cases had a high reported major haemorrhage rate

Elective non-obstetric surgery

All complications 'uncommon' (per 10,000 cases)
10-100

Emergency (urgent and immediate priority) surgery

Share of non-obstetric cases
3454 (16%)
Share of complications
714 (42%)
Severe hypotension, major haemorrhage, severe arrhythmias, septic shock, significant acidosis and electrolyte disturbances 'common' (per 10,000 cases)
100-1000

Factors associated with complications (univariate analysis)

Younger age; higher ASA physical status; male sex; increased frailty; urgency and extent of surgery; day of the week; time of day
  • Univariate analysis

Original publication

The incidence of potentially serious complications during non‐obstetric anaesthetic practice in the United Kingdom: an analysis from the 7th National Audit Project ( NAP7 ) activity survey. Anaesthesia. Published 9 November 2023. doi:10.1111/anae.16155

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