Obstetric anesthesia

Incidence, treatment and outcomes of postpartum haemorrhage among women admitted at a large regional referral hospital in Eastern Uganda: a one-year prospective observational study

Int J Obstet AnesthPublished Prospective observational study

Authors' conclusion

One in 14 women delivered at a large Ugandan hospital developed PPH. Rates of PPH and death are far higher than in high-income countries.

Study context

Population
Women admitted for obstetric care to a large regional referral hospital in eastern Uganda, February 2021 to March 202222.0% of 10,842 deliveries
Participants
2,358 women
Outcome
In-hospital PPH
Methodological detailssingle referral hospital, 166 randomly selected days, direct observation
  • Single referral hospital
  • 166 randomly selected days
  • Direct observation

Main finding

As reported in the abstract

PPH rate

PPH rate 167/2,358

7.1%

Observational data: associations, not effects.

Secondary outcomes

OutcomePPHNo PPHOR (CI)P value
In-hospital maternal mortality, PPH vs no PPH2.4%0.1%26.9 (4.9–147.9)P < 0.0001

Risk factors for PPH (multivariable logistic regression)

OR (CI)P value
Preeclampsia2.25 (1.1–4.6)P = 0.027
Twin pregnancy3.2 (1.7–6.2)P < 0.001
Caesarean deliveryCI as printed0.5 (0.3–09)P = 0.009
Delivery between 4-10 pm0.6 (0.4–0.9)P = 0.032

PPH treatment resources (448 women treated for PPH, incl. 281 delivered elsewhere)

Treated by an obstetrician at the bedside
3.3%
Could have immediately received blood if needed
44.0%
Could have immediately received TXA if needed
47.0%

Original publication

Incidence, treatment and outcomes of postpartum haemorrhage among women admitted at a large regional referral hospital in Eastern Uganda: a one-year prospective observational study. Int J Obstet Anesth. Published 19 June 2025. doi:10.1016/j.ijoa.2025.104707

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