Perioperative medicine & outcomes

Inpatient Postoperative Mortality: Comparing Patients Hospitalized Preoperatively to Those Having Elective Surgery

AnesthesiologyPublished Retrospective cohort study

Main finding · In-hospital deathResult — go to the resultRelative risk 0.13 95% CI 0.12–0.14

Authors' conclusion

Results of previous studies of all-cause perioperative mortality should not be applied to patients having elective major surgery because most deaths (approximately 95%) and most cases (70%) are in patients having nonelective major surgery ( i.e. , already admitted to the hospital or undergoing trauma-related surgery).

Study context

Population
Adults undergoing major diagnostic or therapeutic surgery in Florida in 2021 and 2022, hospitalized 2 or more midnights
Participants
1,245,537 hospitalizations
Exposure
Elective vs nonelective major surgery
Outcome
In-hospital death (share of deaths in the nonelective group)
Methodological detailspopulation-based, statewide administrative data
  • Population-based
  • Statewide administrative data

Main finding

In-hospital death

Relative risk

0.13

95% CI 0.12–0.14

P < 0.0001

By group

Nonelective

94.5%

Elective vs Nonelective
RR 0.13 (95% CI 0.12–0.14); P < 0.0001

As reported in the abstract

Observational data: associations, not effects.

Further findings

Diversity of procedures (ICD-10-PCS codes) among patients who died

Hundreds of different ICD-10-PCS codes occurred commonly among patients who died, in both groups

Safety

AKI, hospital-acquired pneumonia, MACE, infection (sensitivity analyses)

RRs all less than 1.0 in the elective group

Original publication

Inpatient Postoperative Mortality: Comparing Patients Hospitalized Preoperatively to Those Having Elective Surgery. Anesthesiology. Published 27 March 2025. doi:10.1097/aln.0000000000005477

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