Perioperative medicine & outcomes

Inter-Rater Agreement of the Classification of Intraoperative Adverse Events (ClassIntra) in Abdominal Surgery

Ann SurgPublished Inter-rater agreement study

Authors' conclusion

ClassIntra has an almost perfect inter-rater agreement for the classification of iAEs. An increasing grade of ClassIntra was associated with a higher incidence of postoperative complications.

Study context

Population
Elective abdominal surgeries in the LAPAD study
Participants
755 surgeries
Comparison
ClassIntra grading by team 1 vs team 2
Primary endpoint
Inter-rater agreement of ClassIntra grades (Cohen kappa)
Methodological detailssecondary use of data from the LAPAD study, cohort of elective abdominal surgeries
  • Secondary use of data from the LAPAD study
  • Cohort of elective abdominal surgeries

Primary result

As reported in the abstract

Cohen kappa coefficient for ClassIntra grades, 95% CI 0.84-0.90

0.87

IAEs rated in 333 of 755 surgeries by team 1

44%

IAEs rated in 324 of 755 surgeries by team 2

43%

Further findings

Postoperative complications (≥1)

Patients with at least 1 postoperative complication
278 (37%)
Risk of postoperative complications increased with every increase in ClassIntra severity grade

Predictors of postoperative complications

Intraoperative hypotension, MD
23.41 (95% CI 12.93-33.90)
Other organ injuries, MD
18.90 (95% CI −4.22 - 42.02)
  • Strongest predictors

Original publication

Inter-Rater Agreement of the Classification of Intraoperative Adverse Events (ClassIntra) in Abdominal Surgery. Ann Surg. Published 10 January 2023. doi:10.1097/sla.0000000000005024

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