Interaction between bystander sex and patient sex in bystander cardiopulmonary resuscitation for Out-of-Hospital cardiac arrests

Lee, G; Ro, YS; Park, JH; Hong, KJ; Song, KJ; Shin, SD

doi:10.1016/j.resuscitation.2023.109797

Cardiac arrest & resuscitation

Interaction between bystander sex and patient sex in bystander cardiopulmonary resuscitation for Out-of-Hospital cardiac arrests

ResuscitationPublished 18 Apr 2023Retrospective cohort study

Main finding · Bystander CPR provisionResultAdjusted odds ratio 0.62 95% CI 0.58–0.66

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Authors' conclusion

Female bystanders have a lower likelihood of providing bystander CPR than male bystanders. Additionally, an interaction was observed between bystander sex and patient sex in the providing bystander CPR, with the association being more pronounced in male OHCA patients.

Study context

Population: Adult bystander-witnessed out-of-hospital cardiac arrest (OHCA) patients with presumed cardiac etiology, Korea national OHCA registry, January 2016 to December 2020
Participants: 24,919 patients

Exposure: Female vs male bystanders
Outcome: Provision of bystander CPR

Methodological detailsnational registry

National registry

Main finding

Bystander CPR provision

Adjusted odds ratio

0.62

95% CI 0.58–0.66

By group

Female bystanders68.0%

Male bystanders78.8%

Female bystanders vs Male bystanders

adjusted OR 0.62 (95% CI 0.58–0.66)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Outcome	← Lower odds with female bystanders ←→ Higher odds with female bystanders →	OR (CI)
Bystander CPR, CPR-trained bystanders (subgroup)	0.512	0.85 (0.73–0.97)
Bystander CPR by patient sex (interaction analysis)Female bystanders vs Male bystanders · male patients	0.512	0.47 (0.43–0.50)
Bystander CPR by patient sex (interaction analysis)Female bystanders vs Male bystanders · female patients; no significant difference	0.512	0.91 (0.88–1.07)
	0.512Odds ratio (log scale)

Bystander cardiopulmonary resuscitation (CPR) by patient sex (interaction analysis)

Significant difference in likelihood of bystander CPR according to patient sex

Original publication

Interaction between bystander sex and patient sex in bystander cardiopulmonary resuscitation for Out-of-Hospital cardiac arrests. Resuscitation. Published 18 April 2023. doi:10.1016/j.resuscitation.2023.109797

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