Perioperative medicine & outcomes
Intraoperative hypoglycemia among adults with intraoperative glucose measurements: a cross-sectional multicentre retrospective cohort study
Authors' conclusion
In this large cross-sectional retrospective multicentre cohort study, intraoperative hypoglycemia was a rare event. Intraoperative insulin use was not associated with hypoglycemia.
Study context
- Population
- Adults with intraoperative glucose measurements, Multicenter Perioperative Outcomes Group registry, 2015–2019
- Participants
- 516,045 adults
- Outcome
- Intraoperative hypoglycemia (glucose < 3.3 mmol·L-1 [< 60 mg·dL-1])
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
Incidence of intraoperative hypoglycemia
Intraoperative hypoglycemia
3,900
0.76%
Observational data: associations, not effects.
Further findings
Risk factors for intraoperative hypoglycemia
| OR (95% CI) | P value | ||
|---|---|---|---|
| Parenteral nutrition | 0.23 (0.11–0.47) | P < 0.001 | |
| Intraoperative insulin use | 0.996 (0.91–1.09) | P = 0.93 | |
| 0.10.31310Odds ratio (log scale) |
| Outcome | OR | P value |
|---|---|---|
| Risk factors for intraoperative hypoglycemiaAge 18-30 yr vs Every age category above 40 yr | 1.57-3.18 | P < 0.001 |
| Risk factors for intraoperative hypoglycemiaUnderweight or normal weight vs Obesity | 1.48-2.53 | P < 0.001 |
Risk factors for intraoperative hypoglycemia
- DM and CKD more common in the cohort with intraoperative hypoglycemia
Original publication
Intraoperative hypoglycemia among adults with intraoperative glucose measurements: a cross-sectional multicentre retrospective cohort study. Can J Anaesth. Published 13 August 2024. doi:10.
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