Pain medicine

Intrathecal drug delivery systems: an overview of cost-effectiveness evidence

Reg Anesth Pain MedPublished Narrative review of economic evaluations

Authors' conclusion

Most analyses suggest that ITDD is cost-effective compared with conventional management strategies, particularly for cancer-related pain and spasticity.

Study context

Population
Patients with cancer pain, chronic non-cancer pain, or spasticity
Comparison
Intrathecal drug delivery (ITDD) systems vs conventional management strategies
Outcome
Cost-effectiveness of ITDD systems
Methodological detailsoverview
  • Overview

Main finding

As reported in the abstract

Cost-effectiveness
  • Most analyses suggest ITDD is cost-effective vs conventional management, particularly for cancer-related pain and spasticity
  • Robustness limited by methodological heterogeneity and reliance on effectiveness data often from small or uncontrolled studies
  • Evidence for chronic non-cancer pain especially sparse and inconsistent
  • Full and partial economic evaluations, varying perspectives and healthcare settings

Original publication

Intrathecal drug delivery systems: an overview of cost-effectiveness evidence. Reg Anesth Pain Med. Published 8 September 2026. doi:10.1136/rapm-2025-107218

Composed by AI from the published abstract and checked against it. How Briefs are made →

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