ICU sedation, delirium & recovery
Ketamine Analgo-sedation for Mechanically Ventilated Critically Ill Adults: A Rapid Practice Guideline from the Saudi Critical Care Society and the Scandinavian Society of Anesthesiology and Intensive Care Medicine
Methodological detailsGRADE approach, evidence-to-decision framework, multinational multidisciplinary panel
- GRADE approach
- Evidence-to-decision framework
- Multinational multidisciplinary panel
Recommendations
As issued by the authors
- conditional
Suggest against using ketamine as monotherapy analgo-sedation in critically ill adults on invasive mechanical ventilation (iMV) when other analgo-sedatives are available
- conditional
Suggest using ketamine as an adjunct to non-ketamine usual care sedatives (e.g., opioids, propofol, dexmedetomidine) or continuing with non-ketamine usual care sedatives alone
Original publication
Ketamine Analgo-sedation for Mechanically Ventilated Critically Ill Adults: A Rapid Practice Guideline from the Saudi Critical Care Society and the Scandinavian Society of Anesthesiology and Intensive Care Medicine. Anesth Analg. Published 14 July 2025. doi:10.
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