Ketamine versus etomidate as an induction agent for tracheal intubation in critically ill adults: a Bayesian meta-analysis
Pooled resultResult — go to the resultRelative risk 0.93 95% CrI 0.79–1.08Authors' conclusion
This meta-analysis showed a moderate probability that induction with ketamine is associated with a reduced risk of mortality.
Study context
- Population
- Critically ill adults undergoing tracheal intubation7 RCTs, 1 propensity-matched study
- Participants
- 2,978 adults
- Comparison
- Ketamine vs etomidate as induction agent for tracheal intubation
- Ketaminen = 1,475
- Etomidaten = 1,503reference
- Outcome
- Mortality at the longest follow-up available
Methodological detailsBayesian random-effects, weakly informative neutral prior
- Bayesian random-effects
- Weakly informative neutral prior
Pooled result
As reported in the abstract
Relative risk
0.93
95% CrI 0.79–1.08
Events by group
Ketamine vs Etomidate
RR 0.93 (95% CrI 0.79–1.08)
Further pooled results
SOFA score, ventilator-free days, vasopressor-free days, post-induction MAP, first-attempt intubation success
- No significant difference in any secondary outcome
Original publication
Ketamine versus etomidate as an induction agent for tracheal intubation in critically ill adults: a Bayesian meta-analysis. Crit Care. Published 17 February 2024. doi:10.
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