Obstetric anesthesia

Labor epidural analgesia and obstetric and neonatal outcomes in a public tertiary maternity in Uruguay: a retrospective cohort study (2020–2022)

Int J Obstet AnesthPublished Retrospective cohort study

Main finding · Intrapartum cesarean deliveryResult — go to the resultAdjusted odds ratio 1.08 95% CI 0.95–1.24

Authors' conclusion

Labor epidural analgesia was not associated with higher adjusted odds for intrapartum cesarean delivery in this cohort.

Study context

Population
Deliveries at a public tertiary maternity unit (Pereira Rossell Hospital Center, Uruguay), April 2020–December 2022, excluding scheduled or planned cesarean delivery
Participants
10,326 deliveries
Exposure
Labor epidural analgesia vs no labor epidural analgesia
  • Epiduraln = 2,404
Outcome
Intrapartum cesarean delivery
Methodological detailssingle-centre, registry linkage, logistic regression adjusted for maternal age, parity, and labor induction
  • Single-centre
  • Registry linkage
  • Logistic regression adjusted for maternal age, parity, and labor induction

Main finding

As reported in the abstract

Adjusted odds ratio

1.08

95% CI 0.95–1.24

By group

Epidural vs No epidural
aOR 1.08 (95% CI 0.95–1.24)

Observational data: associations, not effects.

Further findings

Operative vaginal delivery and episiotomy

More frequent with epidural analgesia

Any type of perineal laceration

Less frequent with epidural analgesia

Safety

Neonatal Apgar scores

Apgar <7 at 1 and 5 min more frequent with epidural analgesia
No difference in Apgar <4 at 5 min

Original publication

Labor epidural analgesia and obstetric and neonatal outcomes in a public tertiary maternity in Uruguay: a retrospective cohort study (2020–2022). Int J Obstet Anesth. Published 25 March 2026. doi:10.1016/j.ijoa.2026.104925

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