Labor epidural analgesia and obstetric and neonatal outcomes in a public tertiary maternity in Uruguay: a retrospective cohort study (2020–2022)
Main finding · Intrapartum cesarean deliveryResult — go to the resultAdjusted odds ratio 1.08 95% CI 0.95–1.24Authors' conclusion
Labor epidural analgesia was not associated with higher adjusted odds for intrapartum cesarean delivery in this cohort.
Study context
- Population
- Deliveries at a public tertiary maternity unit (Pereira Rossell Hospital Center, Uruguay), April 2020–December 2022, excluding scheduled or planned cesarean delivery
- Participants
- 10,326 deliveries
- Exposure
- Labor epidural analgesia vs no labor epidural analgesia
- Epiduraln = 2,404
- Outcome
- Intrapartum cesarean delivery
Methodological detailssingle-centre, registry linkage, logistic regression adjusted for maternal age, parity, and labor induction
- Single-centre
- Registry linkage
- Logistic regression adjusted for maternal age, parity, and labor induction
Main finding
As reported in the abstract
Adjusted odds ratio
1.08
95% CI 0.95–1.24
By group
Epidural vs No epidural
aOR 1.08 (95% CI 0.95–1.24)
Observational data: associations, not effects.
Further findings
Operative vaginal delivery and episiotomy
- More frequent with epidural analgesia
Any type of perineal laceration
- Less frequent with epidural analgesia
Safety
Neonatal Apgar scores
- Apgar <7 at 1 and 5 min more frequent with epidural analgesia
- No difference in Apgar <4 at 5 min
Original publication
Labor epidural analgesia and obstetric and neonatal outcomes in a public tertiary maternity in Uruguay: a retrospective cohort study (2020–2022). Int J Obstet Anesth. Published 25 March 2026. doi:10. 1016/ j. ijoa. 2026. 104925
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