Landscape of Anesthesiology Perioperative Interventional Clinical Trials Registered in ClinicalTrials.gov
Authors' conclusion
Anesthesiology interventional trials are predominantly small, single-site, randomized studies sponsored by sources other than government or industry.
Study context
- Population
- Perioperative interventional clinical trials registered in ClinicalTrials.gov, 2008–2022trials
- Participants
- 280,793 trials
- Exposure
- Anesthesiology vs nonanesthesiology perioperative interventional trials
- Anesthesiologyn = 6,602
- Outcome
- Trial characteristics
Methodological detailsregistry analysis, Cochrane-Armitage trend tests
- Registry analysis
- Cochrane-Armitage trend tests
Main finding
As reported in the abstract
Proportion of anesthesiology trials, 2008 vs 2022
1.5% to 2.7%
P < 0.001
Observational data: associations, not effects.
Further findings
Sample size, phase 3 or 4 trials
P < 0.0001
Trial duration
P < 0.0001
Sponsorship, global
Industry
Government
Funding, US (subgroup)
Federal
Industry
Research area, anesthesiology trials
- Regional anaesthesia
- 31.3%
- General anaesthesia
- 30.2%
Original publication
Landscape of Anesthesiology Perioperative Interventional Clinical Trials Registered in ClinicalTrials.gov. Anesthesiology. Published 12 September 2025. doi:10.
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