ICU sedation, delirium & recovery
Long-term health outcomes of COVID-19 in intensive care unit (ICU)- and non-ICU-treated patients up to 2 years after hospitalization: a longitudinal cohort study (CO-FLOW)
Authors' conclusion
73% (322/443) of patients had not completely recovered from COVID-19 by 2 years.
Study context
- Population
- Adults surviving hospitalization for COVID-19, followed at 3, 6, 12 and 24 months post-discharge
- Participants
- 650 adults
- Exposure
- ICU-treated vs non-ICU-treated patients
- ICU-treatedn = 273
- Outcome
- Not completely recovered from COVID-19
- Follow-up
- Up to 2 years
Methodological detailsmulticentre, longitudinal
- Multicentre
- Longitudinal
Main finding
As reported in the abstract
Patients not completely recovered from COVID-19 at 2 years
73%
322/443
Observational data: associations, not effects.
Further findings
Symptoms · up to 2 years
- Memory problems
- 274/443; 55%
- Concentration problems
- 259/443; 52%
- Dyspnea
- 251/493; 51%
Other patient-reported outcomes · up to 2 years
- Poor sleep quality
- 61% (259/427)
- Fatigue
- 51% (222/433)
- Cognitive failures
- 23% (102/438)
- Did not fully return to work
- 30% (65/216)
ICU vs non-ICU · up to 2 years
- Most outcomes comparable; ICU tended to slower recovery in neurocognitive symptoms, mental health and resuming work, but more improvement in physical outcomes
Risk factors for poorer outcomes
- Female sex and/or pre-existing pulmonary disease major risk factors
Original publication
Long-term health outcomes of COVID-19 in ICU- and non-ICU-treated patients up to 2 years after hospitalization: a longitudinal cohort study (CO-FLOW). J Intensive Care. Published 8 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →