ICU sedation, delirium & recovery
Long-Term Mental Health Morbidity in Adult Survivors of COVID-19 Critical Illness: A Population-Based Cohort Study
Authors' conclusion
As compared with survival after critical illness resulting from non-COVID-19 pneumonia, survival after COVID-19 critical illness was not associated with increased risk of the composite outcome of new mental health diagnosis, but was associated with elevated risk of new mood, anxiety, or related disorders.
Study context
- Population
- Adult (≥ 18 years) survivors of critical illness, Ontario, Canada, January 1, 2020-March 31, 2022102 centers
- Participants
- 6,098 vs 2,568
- Exposure
- COVID-19 critical illness vs Non-COVID-19 pneumonia
- COVID-19 critical illnessn = 6,098
- Non-COVID-19 pneumonian = 2,568reference
- Outcome
- New mental health diagnosis after hospital discharge (composite of mood, anxiety, or related disorders; schizophrenia or psychotic disorders; other mental health disorders)
Methodological detailsoverlap propensity score-weighted, cause-specific proportional hazard models, 102 centers
- Overlap propensity score-weighted
- Cause-specific proportional hazard models
- 102 centers
Main finding
As reported in the abstract
Hazard ratio
1.08
95% CI 0.96–1.23
By group
COVID-19 critical illness vs Non-COVID-19 pneumonia
HR 1.08 (95% CI 0.96–1.23)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| New mood, anxiety, or related disordersAfter propensity weighting | 1.21 (1.05–1.40) | |
| 0.512Hazard ratio (log scale) |
Psychotic disorders, other mental health diagnoses, social problems, deliberate self-harm
- No difference
Original publication
Long-Term Mental Health Morbidity in Adult Survivors of COVID-19 Critical Illness: A Population-Based Cohort Study. Chest. Published 22 January 2025. doi:10. 1016/ j. chest. 2025. 01. 012
Composed by AI from the published abstract and checked against it. How Briefs are made →