ICU sedation, delirium & recovery

Long-Term Mental Health Morbidity in Adult Survivors of COVID-19 Critical Illness: A Population-Based Cohort Study

ChestPublished Population-based cohort study

Authors' conclusion

As compared with survival after critical illness resulting from non-COVID-19 pneumonia, survival after COVID-19 critical illness was not associated with increased risk of the composite outcome of new mental health diagnosis, but was associated with elevated risk of new mood, anxiety, or related disorders.

Study context

Population
Adult (≥ 18 years) survivors of critical illness, Ontario, Canada, January 1, 2020-March 31, 2022102 centers
Participants
6,098 vs 2,568
Exposure
COVID-19 critical illness vs Non-COVID-19 pneumonia
  • COVID-19 critical illnessn = 6,098
  • Non-COVID-19 pneumonian = 2,568reference
Outcome
New mental health diagnosis after hospital discharge (composite of mood, anxiety, or related disorders; schizophrenia or psychotic disorders; other mental health disorders)
Methodological detailsoverlap propensity score-weighted, cause-specific proportional hazard models, 102 centers
  • Overlap propensity score-weighted
  • Cause-specific proportional hazard models
  • 102 centers

Main finding

As reported in the abstract

Hazard ratio

1.08

95% CI 0.96–1.23

By group

COVID-19 critical illness vs Non-COVID-19 pneumonia
HR 1.08 (95% CI 0.96–1.23)

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
New mood, anxiety, or related disordersAfter propensity weighting1.21 (1.05–1.40)

Psychotic disorders, other mental health diagnoses, social problems, deliberate self-harm

No difference

Original publication

Long-Term Mental Health Morbidity in Adult Survivors of COVID-19 Critical Illness: A Population-Based Cohort Study. Chest. Published 22 January 2025. doi:10.1016/j.chest.2025.01.012

Composed by AI from the published abstract and checked against it. How Briefs are made →

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