ICU sedation, delirium & recovery
Long-term mortality of critically ill patients with cancer and delirium who survived to discharge: a retrospective cohort study
Main finding · One-year mortality after hospital dischargeResult — go to the resultHazard ratio 1.58 95% CI 1.36–1.83Authors' conclusion
We observed that delirium during ICU stay was associated with increased one-year mortality, but was not with mortality after one year.
Study context
- Population
- Adults with cancer admitted to the intensive care unit (ICU) and discharged from hospital, January 2015 to December 2018
- Participants
- 3,079 adults
- Exposure
- Delirium vs no delirium during ICU stay
- Deliriumn = 430
- Outcome
- Long-term mortality (up to three years after discharge)
Methodological detailsadjusted for potential confounders
- Adjusted for potential confounders
Main finding
One-year mortality after hospital discharge · 1 year
Hazard ratio
1.58
95% CI 1.36–1.83
Delirium vs No delirium
HR 1.58 (95% CI 1.36–1.83)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| One to three-year mortality · 1–3 years | 0.92 (0.61–1.39) | |
| One-year mortality by delirium type (hypoactive, mixed)Hypoactive delirium vs No delirium | 1.77 (1.46–2.14) | |
| One-year mortality by delirium type (hypoactive, mixed)Mixed delirium vs No delirium | 1.56 (1.21–2.00) | |
| 0.512Hazard ratio (log scale) |
One to three-year mortality by delirium motor type · 1–3 years
- None of the delirium motor types associated with one to three-year mortality
Original publication
Long-term mortality of critically ill patients with cancer and delirium who survived to discharge: a retrospective cohort study. Can J Anaesth. Published 23 August 2023. doi:10.
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