Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Pulmonary Hypertension
Main findingResult — go to the resultAdjusted odds ratio 0.75 95% CI 0.49–1.15Authors' conclusion
Among pregnant patients with pulmonary hypertension, a trial of labor was not associated with a higher risk of morbidity compared to an intended cesarean delivery.
Study context
- Population
- Patients with pulmonary hypertension delivering ≥25 weeks gestation, Premier inpatient database, January 1, 2016, to September 30, 2020
- Participants
- 727 deliveries
- Exposure
- Intended vaginal delivery vs intended cesarean delivery
- Outcome
- Nontransfusion severe maternal morbidity
- Follow-up
- During the delivery hospitalization
Methodological detailsadministrative database, intention to treat analysis, as treated sensitivity analysis
- Administrative database
- Intention to treat analysis
- As treated sensitivity analysis
Main finding
As reported in the abstract
Adjusted odds ratio
0.75
95% CI 0.49–1.15
Intended vaginal delivery vs Intended cesarean delivery
aOR 0.75 (95% CI 0.49–1.15)
Observational data: associations, not effects.
Secondary outcomes
Blood transfusion (≥4 units)
| aOR (95% CI) | ||
|---|---|---|
| Intended cesarean deliveryNot associated | 0.71 (0.34–1.50) | |
| 0.20.5125Adjusted odds ratio (log scale) |
Readmission · within 90 days
| aOR (95% CI) | ||
|---|---|---|
| Intended cesarean deliveryNot associated | 0.60 (0.32–1.14) | |
| 0.20.5125Adjusted odds ratio (log scale) |
| Outcome | aOR (95% CI) | |
|---|---|---|
| Nontransfusion morbidity, cesarean vs vaginal delivery (as treated sensitivity analysis)As treated analysis | 2.64 (1.54–3.93) | |
| Blood transfusion, cesarean vs vaginal delivery (as treated sensitivity analysis)As treated analysis | 3.06 (1.17–7.99) | |
| Readmission within 90 days, cesarean vs vaginal delivery (as treated sensitivity analysis)As treated analysis | 2.20 (1.09–4.46) | |
| 0.10.31310Adjusted odds ratio (log scale) |
Original publication
Maternal Morbidity According to Mode of Delivery Among Pregnant Patients With Pulmonary Hypertension. Anesth Analg. Published 15 April 2024. doi:10.
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