Measures and Impact of Caseload Surge During the COVID-19 Pandemic: A Systematic Review*
Authors' conclusion
Pandemic caseload surge was associated with lower survival across most studies regardless of jurisdiction, timing, and population.
Study context
- Population
- Hospitalized patients during the COVID-19 pandemic39 studies
- Comparison
- Pandemic caseload surge measures and mortality
- Outcome
- Association between pandemic surge-related measures and mortality in hospitalized patients
Methodological detailssemiquantitative synthesis, 17 of 39 studies in ICU settings; 35 from high-income countries; 31 included patients with COVID-19
- Semiquantitative synthesis
- 17 of 39 studies in ICU settings; 35 from high-income countries; 31 included patients with COVID-19
Pooled result
As reported in the abstract
Caseload surge-mortality association
Studies reporting detrimental adjusted odds/hazard ratio for caseload surge-mortality
32 of 39 studies
82%
Point estimates up to four-fold increased risk of mortality
4
Different surge metrics (mapped into four broad themes)
37
Further pooled results
Subgroups by publication year, patient types, clinical settings, country income status (subgroup)
- Signal persisted among study subgroups
Original publication
Measures and Impact of Caseload Surge During the COVID-19 Pandemic: A Systematic Review*. Crit Care Med. Published 22 March 2024. doi:10.
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